Yoshiharu Uno, MD,PhD
Gas and water will increase in the intestinal tract by a high-FODMAP.
Thereby, it will cause the symptoms of irritable bowel syndrome.
However, the black box exists.

Why increasing of gas and water is lead to IBS symptoms?
What are the mechanisms that produce an alternating bowel movement abnormality?
In the black box, the physiological factors of the intestinal tract might be contains.
Colon sphincters might be an important factor in the black box.
Concerning the colon sphincters, it has been written in the book of the following.




In that study, antispasmodic was not used.
The movement of the large intestine filled with barium was continuously
observed in fuluoroscopy.
Similar studies had been conducted in Europe and the United States in the
1920s. However, these studies had been performed by some of X-ray photography.
Then, double contrast
method was performed: barium and air are infused to the colon, and the
anticonvulsant is injected.
Radiocgraphy of The Large Intestine
Based on Dynamic Observation
In 1958
This book can not be get.



The following
photo is the X-ray picture of IBS on Japanese medical text book in 1981.
Modern medical
diagnostics
Kanehara-
Publishing, 1981

In IBS, colon sphincters are exceedingly contraction.
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7/12/2016: PM19:40
Yoshiharu Uno, ND, PhD
Cannon sphincter would be most important.
By contraction of this sphincter, stool may be stagnation.
Thereby, it may cause constipation.

Burnett FL. Am J Roentgennol, 1923







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