アフリカの豚の便のメタゲノム解析で、多くのウイルスが検出された。
地球に生じるウイルス感染の多くは、 アフリカを起源とするという事実がある。
宇宙からみれば、地球に住む人間は、微小な点に集合する生物に過ぎない。
地球という集団で、感染症「を考えなければ、地球人の健康は保全できない。
In metagenomic analysis of feces of African swine, a lot of the virus has been detected.
Many of the viral infection that occurs in the earth, there is a fact that originated from Africa.
It is necessary to consider the infection at the level of earthlings.
http://www.ncbi.nlm.nih.gov/pubmed/26965436
Arch Virol. 2016
Mar 10. [Epub ahead of print]
Metagenomic analysis demonstrates
the diversity of the fecal virome in asymptomatic pigs in East Africa.
Amimo JO1,2, El Zowalaty ME3, Githae D4, Wamalwa M4, Djikeng A4, Nasrallah GK5,6.
Abstract
Pigs harbor a variety of
viruses that are closely related to human viruses and are suspected to have
zoonotic potential. Little is known about the presence of viruses in
smallholder farms where pigs are in close contact with humans and wildlife.
This study provides insight into viral communities and the prevalence and
characteristics of enteric viral co-infections in smallholder pigs in East
Africa. Sequence-independent amplification and high-throughput sequencing were
applied to the metagenomics analysis of viruses in feces
collected from asymptomatic pigs. A total of 47,213 de novo-assembled contigs
were constructed and compared with sequences from the GenBank database. Blastx
search results revealed that 1039 contigs (>200 nt) were related to viral
sequences in the GenBank database. Of the 1039 contigs, 612 were not assigned
to any viral taxa because they had little similarity to known viral genomic or
protein sequences, while 427 contigs had a high level of sequence similarity to
known viruses and were assigned to viral taxa. The most frequent contigs
related to mammalian viruses resembling members of the viral genera Astrovirus,
Rotavirus, Bocavirus, Circovirus, and Kobuvirus. Other less abundant contigs
were related to members of the genera Sapelovirus, Pasivirus, Posavirus,
Teschovirus and Picobirnavirus. This is the first report on the diversity of
the fecal virome of pig populations in East Africa. The findings of the present
study help to elucidate the etiology of diarrheal diseases in pigs and identify
potential zoonotic and emerging viruses in the region. Further investigations
are required to compare the incidence of these viruses in healthy and diseased
pigs in order to better elucidate their pathogenic role.
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it is necessary to eliminate the disparity of poverty.
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