Office Uno  Column: Yoshiharu Uno



Low FODMAP diet (LFD) is effective for IBS patient.

This is no doubt.

The most important is that the symptoms are reduced after LFD. Thereby, patients can understand that the cause of IBS is not a stress. In LFD, there is no nutritionally nutrients deficiency by alternative food. Continuing LFD, pH in the gut will rise (7.5). This may suppressed the gas-producing bacteria. Many of the gas-producing bacteria is increased in gut of pH 6 ~ 7.

 Certainly, absolute amount of SCFA is reduced by long period of LFD. However, the relative proportions does not decrease. If you are IBS, you choose a painful life by fermentation in the gut? I experienced two IBS with unforgettable. They committed suicide in order to escape from suffering of daily terrible gas symptoms. Nutritionally, LFD is worse than vegetarian meal? In the future, it should be considered the combination therapy of Rifaximin and LFD. Thereby, there is a possibility to reduce the amount of time LFD and Rifaximin dose.